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Syphilis Symptoms & Testing

Cross Street Medical Clinic offers all relevant STD/STI screening tests and treatments. Speak to our doctors today about what you may need. Female doctors are available by appointment. We ensure patient privacy and confidentiality for all discussions, tests and treatments.

What is Syphilis?

Syphilis is a sexually transmitted infection (STI) caused by the bacterium Treponema pallidum.

Syphilis can cause serious complications if left untreated, by spreading to the brain, nerves, eyes, heart, liver, bones and joints.

How do we contract Syphilis?

Syphilis is a highly contagious disease that spreads by direct contact with a syphilis ulcer during vaginal, oral and anal sex.

Occasionally, the disease can be passed to another person through prolonged kissing or close bodily contact.

If you have had syphilis and were treated, you can still get infected again through unprotected sex with someone with syphilis.

How can we tell that we may have Syphilis?

Syphilis is nicknamed the “great pretender” because the symptoms can look like many other diseases.

The average time before appearance of the first symptoms is 21 days but can range from 10 to 90 days.

Typical symptoms include:

  • Firm, painless, non-itchy ulcer or ulcers (chancre) on or around the penis, scrotum, vagina, or anus
  • Painful sores inside vagina, rectum, mouth and lips
  • Reddish-pink, non-itchy rash on the trunk and extremities, including the palms and soles
  • Flat, broad, whitish, wart-like lesions known as condylomata latum on mucous membranes

Testing for Syphilis

Usually, blood tests (VDRL, TPPA, RPR titres) are used to screen and follow-up syphilis treatment.

A screening test, known as a Rapid Syphilis Test Kit (results available after 20 minutes) is also available.

Cross Street Medical
 offers all syphilis screening tests. Speak to our doctors today about what you may need. Female doctors are available by appointment. We ensure patient privacy and confidentiality for all discussions, tests and treatments.

What does Syphilis do to our bodies?

There are four stages:

Primary syphilis
During the first stage, you may notice a single sore or multiple ulcers. The ulcer is located where syphilis entered the body. Sores are usually (but not always) firm, round, and painless and often go unnoticed. There may also be painless lymph nodes.

The sores heal within 3 to 6 weeks. After ulcers heal, you are still infectious unless you have been treated with antibiotics.

Secondary syphilis
During the secondary stage, you may have skin rashes and sores in the mouth, vagina, or anus. The rash can start at one or more areas of the body. The rash can show up when your primary sore is healing or 4-10 weeks after the sore has healed.

The rash can look like rough, red, or reddish brown spots on the palms of your hands and soles of the feet. Other symptoms include fever, swollen lymph glands, sore throat, patchy hair loss, headaches, weight loss, muscle aches, and fatigue.

Symptoms will disappear, even without treatment. But you are still infectious until you have been treated with antibiotics.

Latent syphilis
During the latent stage, there are no visible signs or symptoms of syphilis. This period can last for years, and you remain infectious until you have been treated with antibiotics.

Tertiary syphilis
Most people with untreated syphilis do not develop tertiary syphilis. Tertiary syphilis can occur 3–30 years after infection. In tertiary syphilis, there can be damage to internal organs such as the brain, nerves, eyes, heart, liver, bones and joints.

Untreated syphilis may also increase a person’s risk of HIV.

What is the treatment for Syphilis?

Syphilis infection can be cured with antibiotics.

Follow-up testing for up to 24 months is recommended to confirm that treatment is successful.

Cross Street Medical offers treatment for syphilis. Speak to our doctors today about what you may need. Female doctors are available by appointment. We ensure patient privacy and confidentiality for all discussions, tests and treatments.

How do we prevent infection and re-infection?

  • Avoiding high risk sex, including commercial sex workers, casual sex and multiple sex partners
  • Using condoms, including during oral sex
  • Being in a long-term monogamous relationship with a partner who has tested negative for syphilis and other STDs/STIs

The introduction of the antibiotic, Penicillin in the mid-twentieth century effectively treated Syphilis. This is still the first-line treatment for Syphilis. 

The first reported outbreaks of Syphilis were reported in Europe in 1495 and spread rapidly to other continents, resulting in a pandemic strain of syphilis. 

According to recent scientific research at the University of Zurich, a newer pandemic cluster (called SS14-Ω) emerged after the introduction of antibiotics in the mid-20th century. 

Current Syphilis infections are predominantly from this newer cluster. 

Why is this important? 

Syphilis infections (originating from SS14Ω) are very likely to be resistant to azithromycin, (a second-line antibiotic treatment for Syphilis and other sexually transmitted diseases). 

Much has been written in the news recently about drug-resistant infections, such as Gonorrhoea. 

The drug resistance with Syphilis highlights the importance of correct choice of antibiotics and proper follow-up to ensure that treatment is effective. Incorrect antibiotic use will lead to incomplete cure, recurrence of infection and potential spread of Syphilis to other people. 

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If you have Syphilis, it can be treated effectively with antibiotics. 

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